The members of the Fonds de recherche du Québec – Nature et technologies (FRQNT) Board of Directors are appointed by the Cabinet of the government of Québec. The composition of the Board of Directors reflects the FRQNT's vocation and respects the desired balance between the various scientific fields, institutions and regions, as well as appropriate gender representation. It also expresses the FRQNT's commitment to meeting all of the mandates of its mission: supporting research, researcher training and knowledge mobilization and establishing necessary partnerships.

The FRQNT Board of Directors holds at least four meetings annually.